Group E members of the SOX transcription factor family include SOX8, SOX9, and SOX10.Preceding the high mobility group (HMG) domain in each of these proteins is a thirty-eight amino acid region that supports the formation of dimers on promoters containing tandemly inverted sites.The purpose of this study was to obtain new structural insights into h

Spinal cord enlargement (SCE) includes conditions such as Syringomyelia, tumors, and tumor-like cases of demyelination, edema, or inflammation.These conditions involve fluid-filled cysts, known as syrinx, or masses of tissue, referred to as tumors, which cause increased pressure within the spinal cord (SC) and obstruct cerebrospinal fluid (CSF) cir

Hematophagous insects transmit infectious diseases.Sand flies are vectors of leishmaniasis, but can also transmit viruses.We have been studying immune responses of Lutzomyia longipalpis, the main vector of visceral leishmaniasis in the Americas.We identified a non-specific antiviral response in L.longipalpis LL5 embryonic cells when treated with no

Abstract The adult mammalian brain retains some capacity Hard drive cases and docks to replenish neurons and glia, holding promise for brain regeneration.Thus, understanding the mechanisms controlling adult neural stem cell (NSC) differentiation is crucial.Paradoxically, adult NSCs in the subependymal zone transcribe genes associated with both mult

BACKGROUND:Workplace bullying has diverse consequences at both the organisational and individual level.Anecdotal reports indicate that workplace bullying is an issue of particular concern for Australian FIFO workers, which may impact on psychosocial distress.However, no prior studies have examined this issue empirically in a FIFO worker cohort.METH